AdipoUpX™ Human PLIN2 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PLIN2 MMLV Particle (Overexpression) is a ready-to-use retroviral vector particle professionally engineered for the stable overexpression of the human PLIN2 (ADRP) gene. It is central to the formation and stabilization of lipid droplets in non-adipocytes, making it a primary target for studying hepatic steatosis and foam cell formation. MMLV-mediated integration provides a reliable tool for long-term functional validation in dividing host cells. Every viral product is verified by titer, sterility, and mycoplasma testing to ensure experimental safety and consistency.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: PLIN2

Full Name: Perilipin 2

Gene Symbol: ADFP; ADRP

Gene ID: 123

RefSeq ID-1: NP_001113.2

RefSeq ID-2: NM_001122.3

Summary: PLIN2 encodes a lipid droplet–associated protein that coats intracellular neutral lipid stores and regulates lipid accumulation. Although initially characterized in adipocytes, PLIN2 is broadly expressed in many cell types and tissues, where it serves as a marker of intracellular lipid deposition. Its function in lipid storage and adipose tissue maintenance supports a role in obesity and metabolic disease. Alternative splicing generates multiple transcript variants.

AdipoUpX™ Human PLIN2 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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