AdipoUpX™ Human FGF21 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FGF21 MMLV Particle (Overexpression) is a ready-to-use retroviral vector particle professionally engineered for the stable overexpression of the human FGF21 gene. This hormone is a key regulator of glucose and lipid metabolism with potent insulin-sensitizing effects. MMLV-mediated stable integration ensures a reliable platform for researching FGF21’s role in thermogenesis and energy balance in dividing cells. All viral products undergo comprehensive quality control (titer, sterility, and mycoplasma testing) to ensure both product safety and experimental reproducibility.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: FGF21

Full Name: Fibroblast growth factor 21

Gene ID: 26291

RefSeq ID-1: NP_061986.1

RefSeq ID-2: NM_019113.4

Summary: FGF21 is a secreted endocrine hormone that functions as a master regulator of metabolism. It is produced primarily in the liver and acts on adipose tissue to stimulate glucose uptake and enhance fat burning (thermogenesis). FGF21 is highly sensitive to nutritional status (such as fasting or high-sugar diets) and is being heavily researched as a therapeutic agent to treat obesity and fatty liver disease due to its ability to improve insulin sensitivity.

AdipoUpX™ Human FGF21 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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