AdipoUpX™ Human FASN Ad5 Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FASN Ad5 Adenoviral Particle (Overexpression) enables the efficient transient overexpression of the human FASN gene, which catalyzes the synthesis of long-chain fatty acids. This tool serves as a powerful gene delivery tool for researching fatty acid metabolism and its role in obesity-driven liver dysfunction. Product quality is guaranteed by rigorous purification, titer validation, and comprehensive QC screening.

Production Cell Line: HEK293

Viral Backbone: Adenovirus type5 (dE1/E3)

Promoter: CMV

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: All viral preparations have been validated via PCR to confirm the integrity of their vector genomes.

Sterility Test: This product was confirmed to be sterile upon testing.

Mycoplasma Test: This product has passed quality control, confirming that it is free of mycoplasma contamination.

Other QC: We perform customized supplementary testing and in vitro/in vivo transduction assessments based on specific project requirements to analyze the expression levels and biological functions of transgenes.

Storage: Upon receipt of viral preparations, they must be immediately transferred to a -80°C environment for long-term storage.

Stability: The product guarantees excellent stability for 6-12 months when stored continuously at -80°C (and in some cases, up to 2 years). Upon thawing, the working solution is refrigerated at 4°C for up to 2-3 weeks without significant loss of biological activity.

Shipping Condition: Our adenovirus viral products are shipped using dry ice.

Handling Notes: Viral particles are highly sensitive to temperature fluctuations and freeze-thaw cycles. To maintain titer and avoid repeated freeze-thaw cycles, it is recommended to aliquot the vector immediately upon receipt into low-protein-binding tubes and store according to specified conditions. Ensure all operations are performed within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Our company is committed to product quality, and all products have undergone rigorous internal QC inspections. Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application. Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes.

Target Profile

Gene Name: FASN

Full Name: Fatty acid synthase

Gene Symbol: FAS; OA-519; SDR27X1

Gene ID: 2194

RefSeq ID-1: NP_004095.4

RefSeq ID-2: NM_004104.4

Summary: FASN is a massive, multi-enzyme complex responsible for de novo lipogenesis. It utilizes acetyl-CoA, malonyl-CoA, and NADPH to synthesize palmitate, the foundation for long-chain saturated fatty acids. In the context of obesity, FASN is the primary engine that converts excess carbohydrate energy into storable fat. While critical for energy reserves, its overactivity is a hallmark of metabolic syndrome and has been observed in various oncogenic gene fusions.

AdipoUpX™ Human FASN Ad5 Particle (Overexpression)

Product Overview

Specification

Target Profile

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