AdipoUpX™ Human CIDEA MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CIDEA MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the long-lasting overexpression of the human CIDEA gene. It is a vital regulator of lipid droplet growth and thermogenesis in adipocytes. Because the MMLV particle integrates into the host cell genome, it is perfect for establishing permanent cell lines for energy expenditure research. Every batch is validated through comprehensive quality control screening against contaminants, ensuring the highest standards of safety and efficacy.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: CIDEA

Full Name: Cell death inducing DFFA like effector a

Gene Symbol: CIDE-A

Gene ID: 1149

RefSeq ID-1: NP_001270.1

RefSeq ID-2: NM_001279.4

Summary: CIDEA encodes a lipid droplet–associated protein involved in adipocyte metabolism and apoptosis. Experimental models demonstrate that loss of CIDEA enhances thermogenesis, lipolysis, and resistance to diet-induced obesity, particularly in brown adipose tissue. These findings implicate CIDEA as a negative regulator of energy expenditure.

AdipoUpX™ Human CIDEA MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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