AdipoUpX™ Human CEBPA MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CEBPA MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the efficient and long-lasting overexpression of the human CEBPA gene. This transcription factor is a master regulator of adipocyte differentiation, and its stable expression is essential for studying the transition from preadipocytes to mature fat cells. The MMLV system's stable integration makes it an ideal asset for longitudinal developmental studies. Clients can freely customize key functional components like markers and promoters, while comprehensive quality control ensures high efficacy and safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: CEBPA

Full Name: CCAAT enhancer binding protein alpha

Gene Symbol: CEBP; C/EBP-alpha

Gene ID: 1050

RefSeq ID-1: NP_001272758.1

RefSeq ID-2: NM_001285829.2

Summary: CEBPA is an intronless transcription factor containing a basic leucine zipper (bZIP) domain that binds CCAAT motifs in target gene promoters. It functions as both a homodimer and a heterodimer with other CEBP family members, modulating gene expression in cell cycle regulation and body weight control. Alternative translation initiation produces isoforms of different lengths, and mutations in this gene are associated with acute myeloid leukemia.

AdipoUpX™ Human CEBPA MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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