AdipoUpX™ Human BDNF MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human BDNF MMLV Particle (Overexpression) is a high-titer, ready-to-use MMLV retroviral particle professionally engineered for the stable overexpression of the human BDNF gene. As a critical neurotrophic factor in the regulation of food intake and energy expenditure, its stable integration into dividing cells is an ideal tool for neuroendocrinology research. Our system supports flexible selection of report genes and promoters. To ensure experimental safety, every batch undergoes comprehensive quality control, including titer, sterility, and mycoplasma detection.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: BDNF

Full Name: Brain derived neurotrophic factor

Gene Symbol: ANON2; BULN2

Gene ID: 627

RefSeq ID-1: NP_001137277.1

RefSeq ID-2: NM_001143805.1

Summary: BDNF belongs to the nerve growth factor family and encodes a protein essential for neuronal maintenance. Multiple transcript variants are produced through alternative splicing, and at least one variant yields a precursor protein that is subsequently processed into the active mature form. This protein binds to its specific receptor, supporting neuronal survival in the adult brain. Reduced expression of BDNF is observed in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Additionally, BDNF is implicated in stress response modulation and the regulation of mood-related behaviors.

AdipoUpX™ Human BDNF MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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