Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
AdipoUpX™ Human ACSL1 AAV Particle (Overexpression)
Cat. No.:
V1225XX383
Species:
Human
Target Gene:
ACSL1
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
Add to basket
| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX383-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX383-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX383-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX383-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX383-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX383-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX383-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX383-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX383-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX383-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human ACSL1 AAV Particle (Overexpression) has undergone comprehensive quality control and efficiently expresses the human ACSL1 gene, a key regulator of fatty acid "priming" for oxidation or storage. This makes it an ideal tool for studying the metabolic balance of lipid utilization. Our platform offers highly customizable services, allowing clients to select cell-specific promoters and reporter genes for precise targeting. Safety and reliability are guaranteed through rigorous titer, sterility, and mycoplasma detection performed on every batch.
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
ACSL1
Full Name:
Acyl-CoA synthetase long chain family member 1
Gene Symbol:
ACS1; LACS; FACL1; FACL2; LACS1; LACS2
Gene ID:
2180
RefSeq ID-1:
NP_001273637.1
RefSeq ID-2:
NM_001286708.2
Summary:
ACSL1 encodes a member of the long-chain acyl-CoA synthetase family that catalyzes the activation of long-chain fatty acids into fatty acyl-CoA esters. Although individual isozymes differ in substrate specificity, cellular localization, and tissue expression, all members of this enzyme family are essential for coordinating lipid synthesis and fatty acid oxidation. ACSL1 is particularly relevant to obesity, as it influences whether fatty acids are directed toward storage or degradation in adipose tissue, muscle, and liver. Dysregulation of ACSL1 can promote lipid accumulation and metabolic imbalance. Several alternatively spliced transcript variants have been identified.
Related Products
-
AdipoUpX™ Human KCNJ5 AAV Particle (Overexpression)
-
LipoKnoxa™ Human TUB shRNA AAV Particle (Silencing)
-
AdipoUpX™ Human MYT1L AAV Particle (Overexpression)
-
AdipoUpX™ Human ADIPOR2 AAV Particle (Overexpression)
-
LipoKnoxa™ Human ATF6 shRNA AAV Particle (Silencing)
-
LipoKnoxa™ Human PTEN shRNA AAV Particle (Silencing)