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Silodosin
Cat. No.:
0225LY-1192
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
Add to basket
Product Overview
Description:
Silodosin is an alpha-adrenergic blocker that functions as a selective antagonist to alleviate symptoms related to the adrenergic system.
Synonym:
KAD 3213; KMD 3213; 160970-54-7; Silodosin; Rapaflo; Urief; Silodyx; Urorec; KMD-3213; Rapilif; Silodal; Rapflo; KAD-3213; KMD 3213; 1-(3-hydroxypropyl)-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide; 1H-Indole-7-carboxamide, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-; 1-(3-hydroxypropyl)-5-[(2r)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1h-indole-7-carboxamide; 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide; (R)-1-(3-hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide
CAS No.:
160970-54-7
Compound CID:
5312125
Formula:
C25H32F3N3O4
Formula Weight:
495.53
Specification
Targets&IC50:
α1D-adrenoceptor: 2 nM (Ki); α1A-adrenoceptor: 0.036 nM (Ki); α1B-adrenoceptor: 21 nM (Ki)
Relative Density:
1.249 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Silodosin can be used in urology to investigate the high-selectivity antagonism of alpha-1A adrenergic receptors in the prostate.
Library Information
Target:
β-Adrenergic receptor
Receptor:
GPCR
Pathways:
Neuronal signaling; GPCR/G protein signaling
Plate Number:
AOCL-16
Plate Location:
c9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
92 mg/mL; 185.66 mM
Ethanol Max Solubility:
92 mg/mL; 185.66 mM
