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SB225002
Cat. No.:
0225LY-1146
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
SB225002 is a selective and potent CXCR2 antagonist that prevents interleukin IL-8 from binding to its receptor.
Synonym:
182498-32-4; sb 225002; 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea; SB-225002; N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea; N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea; Urea, N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-; 3-(2-bromophenyl)-1-(2-hydroxy-4-nitrophenyl)urea; 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea.
CAS No.:
182498-32-4
Compound CID:
3854666
Formula:
C13H10BrN3O4
Formula Weight:
352.14
Specification
Targets&IC50:
CXCR2: 22 nM
Relative Density:
1.793 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SB225002 can be used in immunology to investigate the potent and selective antagonism of the CXCR2 chemokine receptor.
Library Information
Target:
CXCR2
Receptor:
CXCR2
Pathways:
GPCR/G protein signaling; Autophagy; Immunology/Inflammation
Plate Number:
AOCL-15
Plate Location:
g2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
71.4 mg/mL; 202.76 mM
Ethanol Max Solubility:
3 mg/mL; 8.52 mM
