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Rat serine palmitoyltransferase; long chain base subunit 3 (SPTLC3) ELISA kit

Cat. No.: 0126WXX-1844
Assay Type: Quantitative ELISA
Target Species: Rat
Assay Target: SPTLC3
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Rat serine palmitoyltransferase; long chain base subunit 3 (SPTLC3) ELISA kit
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Product Overview

Description: Rat serine palmitoyltransferase; long chain base subunit 3 (SPTLC3) ELISA kit is an ELISA-based in vitro research tool designed specifically for the quantitative detection of SPTLC3 in rat samples. The kit is highly sensitive and easy to use.
Assay Principle: The ELISA analytical biochemical technique is based on SPTLC3 antibody-SPTLC3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SPTLC3 antigen targets in samples.
Background: Serine palmitoyltransferase long chain base subunit 3 (SPTLC3) is a key enzyme subunit of serine palmitoyltransferase, the rate-limiting enzyme in sphingolipid biosynthesis. SPTLC3 catalyzes the condensation of serine with fatty acyl-CoA to produce long-chain base sphingoid intermediates, which are essential for the generation of complex sphingolipids involved in cell membrane structure and signaling. Proper SPTLC3 activity is critical for lipid homeostasis, while dysregulation can lead to altered sphingolipid metabolism, contributing to impaired adipocyte function, lipid accumulation, and the development of obesity and obesity-related metabolic disorders.
Synonyms: SPTLC2L; Long chain base biosynthesis protein 3; SPT 3; LCB 3; C20orf38; Aminotransferase 2; Serine-palmitoyl-CoA transferase 3
Applications: Rat serine palmitoyltransferase, long chain base subunit 3 (SPTLC3) ELISA kit is used to quantify SPTLC3 in rat samples, providing data to support research in a wide range of areas, including enzyme and kinase, obesity, and others.
Research Area: Enzyme & Kinase; Obesity

Specification

Sample Type: Rat samples
Cross-reactivity: No significant cross-reactivity or interference was observed.
Storage: Store at 2-8°C.

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