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Rat Niemann-Pick C1 protein ELISA kit-Quantitative competitive

Cat. No.: 0126WXX-1122
Assay Type: Quantitative competitive ELISA
Target Species: Rat
Assay Target: Niemann-Pick C1 protein
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Rat Niemann-Pick C1 protein ELISA kit-Quantitative competitive
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Product Overview

Description: Rat Niemann-Pick C1 protein ELISA kit-Quantitative competitive is an ELISA-based in vitro research tool designed specifically for the quantitative detection of Niemann-Pick C1 protein in rat samples with a range of 0.5-10 ng/mL and a minimum detectable dose (sensitivity) of 0.1 ng/mL. The kit is highly sensitive and easy to use.
Assay Principle: The ELISA analytical biochemical technique is based on Niemann-Pick C1 protein antibody-Niemann-Pick C1 protein antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Niemann-Pick C1 protein antigen targets in samples.
Background: NPC1 is a transmembrane protein localized to the late endosomal/lysosomal membrane, whose core physiological function involves cholesterol and lipid transport and homeostasis regulation within cells. Defects in NPC1 function lead to Niemann-Pick disease type C (NPC), a rare hereditary neurodegenerative disorder characterized by abnormal accumulation of cholesterol and specific lipids within lysosomes. Research has also revealed a potential link to obesity.
Synonyms: Niemann-Pick disease, type C1; NPC1
Applications: Rat Niemann-Pick C1 protein ELISA kit-Quantitative competitive is used to quantify Niemann-Pick C1 protein in serum, plasma, cell culture supernatants, body fluid, tissue homogenate of rat, providing data to support research in a wide range of areas, including neurobiology, obesity, etc.
Research Area: Neurobiology; Obesity

Specification

Sample Type: Serum; Plasma; Cell culture supernatants; Body fluid; Tissue homogenate
Detection Range: 0.5-10 ng/mL
Sensitivity: 0.1 ng/mL
Cross-reactivity: No significant cross-reactivity or interference was observed.
Storage: Store at 2-8°C.

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