Pardoprunox hydrochloride

Cat. No.: 0225LY-1203

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Pardoprunox hydrochloride is a novel pharmacological agent that serves as a partial agonist for dopamine D2 (pKi = 8.1) and D3 (pKi = 8.6) receptors, while acting as a full agonist for the serotonin 5-HT1A receptor (pKi = 8.5).

Synonym: SLV-308 hydrochloride; DU-126891 hydrochloride; 269718-83-4; Pardoprunox HCl; 2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-, monohydrochloride; SME-308; Pardoprunox (hydrochloride); DU-126891 hydrochloride; 7-(4-methylpiperazin-1-yl)-3H-1,3-benzoxazol-2-one;hydrochloride; Pardoprunox (SLV-308) hydrochloride; 7-(4-methylpiperazin-1-yl)-3H-1,3-benzoxazol-2-one hydrochloride; 7-(4-Methylpiperazin-1-yl)-1,3-benzoxazol-2(3H)-one monohydrochloride; 2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-, hydrochloride (1:1); 7-(4-Methylpiperazin-1-yl)benzo[d]oxazol-2(3H)-one hydrochloride

CAS No.: 269718-83-4

Compound CID: 6918524

Formula: C₁₂H₁₆ClN₃O₂

Formula Weight: 269.73

Specification

Targets&IC50: D3 receptor: 8.6(pKi); 5-HT1A receptor: 8.5 (pKi); D2 receptor: 8.1(pKi )

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Pardoprunox hydrochloride can be used in neuroscience to explore the partial agonism of dopamine D2 and D3 receptors and their role in treating movement disorders.