Inquiry
Products
Online Inquiry

Please note that we are not a pharmacy or clinic, so we are unable to see patients and do not offer diagnostic and treatment services for individuals.

Vitamin B12 test kit

LipoKnoxa™ Human CD5L shRNA AAV Particle (Silencing)

Cat. No.: V0126XX419
Species: Human
Target Gene: CD5L
Vector System: AAV
Modulation Type: Silencing (shRNA)
LipoKnoxa™ Human CD5L shRNA AAV Particle (Silencing)
INQUIRY Datasheet MSDS
SPECIFIC INQUIRY
Fluorescent Reporters:
Titer:
Size:
Add to basket
Sub Cat. No. AAV Serotype Tissue Tropism TargetSeq Region Inquiry
V0126XX419-1 AAV1 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-2 AAV1 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-3 AAV1 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-4 AAV2 CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-5 AAV2 CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-6 AAV2 CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-7 AAV3 Lung; Liver; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-8 AAV3 Lung; Liver; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-9 AAV3 Lung; Liver; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-10 AAV4 CNS; Retina; Heart; Lung; Kidney TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-11 AAV4 CNS; Retina; Heart; Lung; Kidney TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-12 AAV4 CNS; Retina; Heart; Lung; Kidney TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-13 AAV5 CNS; Brain; Retina; Heart; Lung; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-14 AAV5 CNS; Brain; Retina; Heart; Lung; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-15 AAV5 CNS; Brain; Retina; Heart; Lung; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-16 AAV6 Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-17 AAV6 Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-18 AAV6 Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-19 AAV7 CNS; Brain; Retina; Liver; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-20 AAV7 CNS; Brain; Retina; Liver; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-21 AAV7 CNS; Brain; Retina; Liver; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-22 AAV8 CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-23 AAV8 CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-24 AAV8 CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-25 AAV9 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle TACTAATCTAGGTCCTATTAC 3' UTR Inquiry
V0126XX419-26 AAV9 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle TCATCTGCTCAGGATAGTATC CDS Inquiry
V0126XX419-27 AAV9 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle TGATTATCCTCATACTCATTC 3' UTR Inquiry
V0126XX419-28 Other Inquiry

Product Overview

Description: LipoKnoxa™ Human CD5L shRNA AAV Particle (Silencing) targets a secreted protein that regulates lipid synthesis in adipocytes and modulates inflammatory responses. Engineered with both U6 and miR30-based shRNA frameworks, this tool helps researchers study the intersection of lipogenesis and immunity. Multiple AAV serotypes are provided to ensure optimal delivery. To guarantee experimental reliability, every preparation undergoes total QC verification—covering functional titer, sequence identity, and sterility.
Production Cell Line: HEK293
AAV ITR: AAV2 ITR
Promoter: U6; CMV; EF1α; CAG; UBC
Product Availability: Produced Upon Order

Specification

Titer Test: qPCR
Insert Verification: The sequence identity and genomic integrity of all preparations were successfully confirmed via sequencing and PCR validation.
Sterility Test: Stringent QC assays have verified the sterility of this product lot, ensuring it is free of all detectable microbial contaminants.
Mycoplasma Test: Confirmed free of mycoplasma contamination via high-sensitivity QC assays; this product lot has successfully passed the production safety protocols.
Other QC: Tailored supplementary testing and transduction performance assays are available to evaluate gene silencing at the molecular level. We provide comprehensive in vitro and in vivo assessments to elucidate the impact of shRNA-targeted editing on gene expression profiles and downstream biological phenotypes.
Storage: To maintain optimal viral potency and structural integrity, it is essential to store the vector at -80°C immediately following its receipt.
Stability: Long-term storage at -80°C ensures product integrity for up to 24 months. For immediate experimental use, the thawed viral preparations are refrigerated at 4°C, maintaining robust performance for a period of 2–3 weeks.
Shipping Condition: Shipped on dry ice. Product integrity is guaranteed through temperature-controlled logistics for all viral vector types.
Handling Notes: To prevent titer loss caused by repeated freeze-thaw cycles, we recommend aliquoting the virus into single-use volumes upon receipt. Use low-protein-binding microcentrifuge tubes and store under specified conditions. Strict adherence to biosafety protocols is required; perform all handling within a designated biosafety cabinet.
Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer: All products undergo stringent quality control; however, no warranty is provided for performance in specific applications, given the diversity of experimental variables. The user is ultimately responsible for ensuring proper storage, handling, and adherence to all local laws, biosafety standards, and safety regulations throughout the use of the product.

Target Profile

Gene Name: CD5L
Full Name: CD5 molecule like
Gene Symbol: AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA
Gene ID: 922
RefSeq ID-1: NP_001334627.1
RefSeq ID-2: NM_001347698.1
Summary: CD5L is involved in immune defense and the regulation of complement activation. It is predicted to function upstream of complement-dependent cytotoxicity and is localized at the cell surface. In obesity, CD5L has been implicated in macrophage activity within adipose tissue, linking immune regulation to lipid metabolism and inflammation.

Related Products

Inquiry
0
Inquiry Basket

Recognizing the multifaceted nature of obesity, we leverage our expertise in preclinical research to provide tailored solutions that address the unique challenges faced by our partners in the biotechnology and pharmaceutical industries.

By Molecule Type

By Products

By Services

Contact Us

Copyright © Protheragen. All rights reserves.