Human sterol regulatory element-binding transcription factor 1 (SREBF1) kit-Quantitative sandwich

Cat. No.: 0126WXX-1846

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: SREBF1

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Human sterol regulatory element-binding transcription factor 1 (SREBF1) kit-Quantitative sandwich

INQUIRY Datasheet MSDS

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Product Overview

Description: Human sterol regulatory element-binding transcription factor 1 (SREBF1) kit-Quantitative sandwich is an ELISA-based in vitro research tool designed specifically for the quantitative detection of SREBF1 in human samples with a range of 12.5-800 ng/mL and a minimum detectable dose (sensitivity) of 3.12 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on SREBF1 antibody-SREBF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SREBF1 antigen targets in samples.

Background: SREBF1 is a key regulator of intracellular lipid and cholesterol synthesis pathways. It primarily functions by controlling the expression of a series of genes involved in fatty acid, triglyceride, and cholesterol synthesis. The activity of SREBF1 is finely regulated by intracellular sterol and insulin signaling and is implicated in pathological processes such as obesity.

Synonyms: BHLHD1; SREBP-1; Sterol regulatory element-binding protein 1; Class D basic helix-loop-helix protein 1; bHLHd1

Applications: Human sterol regulatory element-binding transcription factor 1 (SREBF1) kit-Quantitative sandwich is used to quantify SREBF1 in serum, plasma, cell culture supernatant, and tissue homogenates of human, providing data to support research in a wide range of areas, including lipid metabolism, signal transduction, obesity, and others.

Research Area: Lipid metabolism; Signal transduction; Obesity

Specification

Sample Type: Serum; Plasma; Cell culture supernatants; Tissue homogenates

Detection Range: 12.5-800 ng/mL

Sensitivity: 3.12 ng/mL

Precision (Intra-assay): CV<8%

Precision (Inter-assay): CV<10%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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