Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14) ELISA kit (0.25-8 ng/mL)

Cat. No.: 0126WXX-990

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: MAP3K14

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Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14) ELISA kit (0.25-8 ng/mL)

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Product Overview

Description: Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14) ELISA kit (0.25-8 ng/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of MAP3K14 in human samples with a range of 0.25-8 ng/mL and a minimum detectable dose (sensitivity) of 0.1 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on MAP3K14 antibody-MAP3K14 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MAP3K14 antigen targets in samples.

Background: MAP3K14 is a serine/threonine protein kinase and a critical activator of the non-canonical NF-κB signaling pathway. The link between MAP3K14 and obesity research occurs via chronic inflammation: the obesity-induced chronic inflammatory state (driven by adipocyte stress and macrophage infiltration) relies on sustained activation of the NF-κB pathway. By activating this pathway, MAP3K14 participates in regulating adipose tissue inflammation and insulin resistance, serving as a central link connecting obesity and inflammatory signaling.

Synonyms: HS; NIK; HSNIK; FTDCR1B; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK

EC NO.: 2.7.11.25

Applications: Human mitogen-activated protein kinase kinase kinase 14 (MAP3K14) ELISA kit (0.25-8 ng/mL) is used to quantify MAP3K14 in serum, plasma, whole blood, tissue, saliva, urine, feces, and other fluids of human, providing data to support research in a wide range of areas, including signal transduction, inflammation, obesity, etc.

Research Area: Signal transduction; Inflammation; Obesity

Specification

Sample Type: Serum; Plasma; Whole blood; Other fluid; Tissue; Saliva; Urine; Feces

Detection Range: 0.25-8 ng/mL

Sensitivity: 0.1 ng/mL

Precision (Intra-assay): CV<15%

Precision (Inter-assay): CV<15%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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