Human Helix loop helix protein 2 (NHLH2) ELISA kit-Quantitative competitive

Cat. No.: 0126WXX-1092

Assay Type: Quantitative competitive ELISA

Target Species: Human

Assay Target: NHLH2

Size:

Human Helix loop helix protein 2 (NHLH2) ELISA kit-Quantitative competitive

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Human Helix loop helix protein 2 (NHLH2) ELISA kit-Quantitative competitive is an ELISA-based in vitro research tool designed specifically for the quantitative detection of NHLH2 in human samples with a range of 10-250 ng/mL and a minimum detectable dose (sensitivity) of 1.0 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on NHLH2 antibody-NHLH2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NHLH2 antigen targets in samples.

Background: NHLH2 is a basic helix-loop-helix (bHLH) transcription factor primarily expressed in the central nervous system (especially the hypothalamus) and neuroendocrine tissues. It regulates the differentiation, development, and gene expression of neuroendocrine cells. NHLH2 is a key factor in the central regulation of energy homeostasis, and its relevance to obesity research lies in its profound effects on appetite and energy expenditure. Research indicates that NHLH2 participates in regulating the expression of neuropeptides affecting satiety (such as POMC) in the hypothalamus. Its functional loss or defects lead to hyperphagia, reduced energy expenditure, and severe obesity with associated metabolic syndrome in experimental animals, demonstrating that the NHLH2 signaling pathway serves as a central hub in weight regulation.

Synonyms: Class A basic helix-loop-helix protein 34; bHLHa34; Nescient helix loop helix 2; NSCL-2; HEN2; KIAA0490

Applications: Human Helix loop helix protein 2 (NHLH2) ELISA kit-Quantitative competitive is used to quantify NHLH2 in serum, plasma, cell culture supernatants, body fluid, and tissue homogenate of human, providing data to support research in a wide range of areas, including neuroendocrinology, developmental biology, transcriptional regulation, energy balance, obesity, etc.

Research Area: Neuroendocrinology; Developmental Biology; Transcriptional Regulation; Energy balance; Obesity

Specification

Sample Type: Serum; Plasma; Cell culture supernatants; Body fluid; Tissue homogenate

Detection Range: 10-250 ng/mL

Sensitivity: 1.0 ng/mL

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

Related Products

Inquiry

Inquiry Basket

Delete selected Check Out