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GSK0660
Cat. No.:
0225LY-0903
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
GSK0660 functions as both an inverse agonist and an antagonist specifically for the PPARβ/δ receptor.
Synonym:
1014691-61-2; GSK 0660; Methyl 3-[(4-anilino-2-methoxyphenyl)sulfamoyl]thiophene-2-carboxylate; GSK-0660; Methyl 3-(N-(2-methoxy-4-(phenylamino)phenyl)sulfamoyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester; MFCD12828770
CAS No.:
1014691-61-2
Compound CID:
46233311
Formula:
C19H18N2O5S2
Formula Weight:
418.49
Specification
Targets&IC50:
PPARβ/δ: 155 nM
Relative Density:
1.413 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GSK0660 can be used in nuclear receptor studies to evaluate its function as a selective and potent antagonist of PPAR-delta.
Library Information
Target:
PPAR
Receptor:
PPARβ; PPARδ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
f2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
117.5 mg/mL; 280.77 mM
Ethanol Max Solubility:
4.19 mg/mL; 10.01 mM
ALogP:
3.66
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
8
