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Vitamin B12 test kit

Apilimod

Cat. No.: 0225LY-0773
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
Apilimod
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Product Overview

Description: Apilimod is used in psoriasis research to reduce dendritic cell infiltration and inhibit the production of IL-23 and IL-12.
Synonym: 541550-19-0; N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine; 4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine; N-[(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine; 4-(6-((E)-2-((3-methylphenyl)methylidene)hydrazin-1-yl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine
CAS No.: 541550-19-0
Compound CID: 10173277
Formula: C23H26N6O2
Formula Weight: 418.49

Specification

Targets&IC50: PIKfyve: 14 nM
Relative Density: 1.24 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Apilimod can be used in virology and immunology research to investigate the inhibition of PIKfyve and its effect on viral entry and cytokine production.

Library Information

Target: IL receptor; PIKfyve
Receptor: IL-12; IL-23; PIKfyve
Pathways: Immunology/Inflammation; PI3K/Akt/mTOR signaling
Plate Number: AOCL-11
Plate Location: a2
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 200 mg/mL; 477.91 mM
ALogP: 4.485
HBA_Count: 6
HBD_Count: 1
Rotatable Bond: 8
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