AdipoUpX™ Human UCP1 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human UCP1 MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the stable overexpression of the human UCP1 gene. This hallmark protein of brown fat is the primary driver of non-shivering thermogenesis. Due to its stable integration into the genome, this MMLV particle is perfect for establishing stable adipocyte lines to study browning and energy dissipation. Clients can freely customize markers and functional components, and all products are verified through comprehensive quality control for efficacy and purity.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: UCP1

Full Name: Uncoupling protein 1

Gene Symbol: UCP; SLC25A7

Gene ID: 7350

RefSeq ID-1: NP_068605.1

RefSeq ID-2: NM_021833.5

Summary: UCP1 encodes a mitochondrial uncoupling protein that plays a central role in thermogenesis. It belongs to the mitochondrial anion carrier protein (MACP) family and uncouples oxidative phosphorylation from ATP synthesis, allowing energy to be released as heat via proton leak. UCP1 also facilitates transmembrane transfer of anions and protons, lowering the mitochondrial membrane potential. Unlike other UCP family members, UCP1 expression is restricted to brown adipose tissue, a specialized organ designed for heat production and energy expenditure.

AdipoUpX™ Human UCP1 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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