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AdipoUpX™ Human TP53INP2 AAV Particle (Overexpression)
Cat. No.:
V1225XX378
Species:
Human
Target Gene:
TP53INP2
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX378-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX378-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX378-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX378-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX378-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX378-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX378-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX378-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX378-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX378-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human TP53INP2 AAV Particle (Overexpression) is a ready-to-use viral particle product that achieves stable and efficient expression of the human TP53INP2 gene. This protein promotes autophagy and modulates the activity of thyroid hormone receptors, making it an ideal tool for studying metabolic rate regulation. All viral products undergo rigorous internal quality control to ensure reliability. Our customizable platform also allows for the flexible selection of serotypes for precise targeted delivery.
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
TP53INP2
Full Name:
Tumor protein p53 inducible nuclear protein 2
Gene Symbol:
DOR; PIGU; PINH; PIG-U; C20orf110; dJ1181N3.1
Gene ID:
58476
RefSeq ID-1:
NP_001316358.1
RefSeq ID-2:
NM_001329429.2
Summary:
TP53INP2 encodes a multifunctional regulator of autophagy that is required for autophagosome formation and maturation. By supporting autophagic flux and transcriptional regulation, TP53INP2 contributes to metabolic flexibility and lipid homeostasis under obese conditions.
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