Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
AdipoUpX™ Human PPARA AAV Particle (Overexpression)
Cat. No.:
V1225XX273
Species:
Human
Target Gene:
PPARA
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
Add to basket
| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX273-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX273-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX273-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX273-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX273-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX273-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX273-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX273-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX273-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX273-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human PPARA AAV Particle (Overexpression) has undergone comprehensive quality control and efficiently expresses the human PPARA gene. As a master regulator of fatty acid oxidation, it is an ideal tool for studying hepatic lipid metabolism and energy expenditure. Our platform offers highly customizable services, allowing clients to select from multiple AAV serotypes and cell-specific promoters for precise targeting, with safety ensured by full QC screening (titer, sterility, and mycoplasma).
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
PPARA
Full Name:
Peroxisome proliferator activated receptor alpha
Gene Symbol:
PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha
Gene ID:
5465
RefSeq ID-1:
NP_001001928.1
RefSeq ID-2:
NM_001001928.4
Summary:
PPARA encodes a nuclear transcription factor that acts as a major sensor for dietary lipids. Part of the steroid hormone receptor superfamily, it is activated by fatty acids and hypolipidemic drugs. Once activated, it drives the expression of genes involved in fatty acid oxidation and lipid transport. As a primary regulator of energy mobilization, PPARA is essential for preventing lipid accumulation in the liver and maintaining systemic metabolic health.
Related Products
-
AdipoUpX™ Human POMC AAV Particle (Overexpression)
-
AdipoUpX™ Human PRKAA1 AAV Particle (Overexpression)
-
AdipoUpX™ Human KCNJ11 AAV Particle (Overexpression)
-
AdipoUpX™ Human GHSR AAV Particle (Overexpression)
-
AdipoUpX™ Human ADRB2 AAV Particle (Overexpression)
-
AdipoUpX™ Human FOXO1 AAV Particle (Overexpression)