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AdipoUpX™ Human PLIN2 AAV Particle (Overexpression)
Cat. No.:
V1225XX365
Species:
Human
Target Gene:
PLIN2
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX365-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX365-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX365-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX365-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX365-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX365-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX365-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX365-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX365-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX365-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human PLIN2 AAV Particle (Overexpression) is engineered for the efficient and stable overexpression of the human PLIN2 gene in mammalian cells. This tool is essential for studying the coating of lipid droplets and the regulation of intracellular fat storage. Our AAV platform offers the benefit of high customization, allowing for the flexible selection of cell-specific promoters. Every viral lot undergoes rigorous purification and QC validation (titer and sterility) to ensure the highest standards for lipid droplet research.
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
PLIN2
Full Name:
Perilipin 2
Gene Symbol:
ADFP; ADRP
Gene ID:
123
RefSeq ID-1:
NP_001113.2
RefSeq ID-2:
NM_001122.3
Summary:
PLIN2 encodes a lipid droplet–associated protein that regulates intracellular lipid storage. Widely expressed across tissues, PLIN2 marks lipid accumulation in both adipose and non-adipose cells. Its elevated expression is associated with increased fat storage and metabolic disorders, underscoring its relevance to obesity and ectopic lipid deposition. Alternative splicing generates multiple isoforms.
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