AdipoUpX™ Human FABP2 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FABP2 MMLV Particle (Overexpression) is a high-titer, ready-to-use MMLV retroviral particle professionally engineered for the stable overexpression of the human FABP2 gene. Localized primarily in the small intestine, it is a key target for studying dietary fatty acid absorption and systemic lipid levels. Stable genomic integration in dividing cells provides a robust platform for metabolic research. Our modular system allows for flexible selection of report genes, and every batch passes comprehensive quality control screening to ensure experimental reliability.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: FABP2

Full Name: Fatty acid binding protein 2

Gene Symbol: FABPI; I-FABP

Gene ID: 2169

RefSeq ID-1: NP_000125.2

RefSeq ID-2: NM_000134.4

Summary: FABP2 produces an intracellular protein essential for the absorption and movement of long-chain fatty acids within the intestine. It functions as a high-affinity carrier for saturated fats, facilitating their uptake and subsequent metabolism. Beyond its role in transport, FABP2 serves as a lipid sensor that helps maintain systemic energy homeostasis. Variations in this gene can alter the efficiency of dietary fat absorption, making it a key factor in the study of metabolic rate and diet-induced obesity.

AdipoUpX™ Human FABP2 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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