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AdipoUpX™ Human CIDEC AAV Particle (Overexpression)

Cat. No.: V1225XX293
Species: Human
Target Gene: CIDEC
Vector System: AAV
Modulation Type: Overexpression
AdipoUpX™ Human CIDEC AAV Particle (Overexpression)
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Sub Cat. No. AAV Serotype Tissue Tropism Inquiry
V1225XX293-1 AAV1 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle Inquiry
V1225XX293-2 AAV2 CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle Inquiry
V1225XX293-3 AAV3 Lung; Liver; Smooth muscle Inquiry
V1225XX293-4 AAV4 CNS; Retina; Heart; Lung; Kidney Inquiry
V1225XX293-5 AAV5 CNS; Brain; Retina; Heart; Lung; Smooth muscle Inquiry
V1225XX293-6 AAV6 Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle Inquiry
V1225XX293-7 AAV7 CNS; Brain; Retina; Liver; Smooth muscle Inquiry
V1225XX293-8 AAV8 CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle Inquiry
V1225XX293-9 AAV9 CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle Inquiry
V1225XX293-10 Other Inquiry

Product Overview

Description: AdipoUpX™ Human CIDEC AAV Particle (Overexpression) has undergone comprehensive quality control and efficiently expresses the human CIDEC gene. As a critical regulator of lipid droplet size and triglyceride storage, it is an ideal tool for studying the molecular architecture of fat storage in adipocytes. Our platform offers highly customizable services, including adipose-specific promoters for precise targeting, with safety ensured by full QC screening (titer, sterility, and mycoplasma).
Production Cell Line: HEK293
AAV ITR: AAV2 ITR
Promoter: CMV (default); Other universal or cell-specific promoters
Product Availability: Produced Upon Order

Specification

Titer Test: qPCR
Insert Verification: Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test: The QC assay verified the sterility of this product lot.
Mycoplasma Test: The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC: Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage: Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability: Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition: Our AAV viral products are shipped using dry ice.
Handling Notes: To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer: Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.

Target Profile

Gene Name: CIDEC
Full Name: Cell death inducing DFFA like effector c
Gene Symbol: CIDE3; FPLD5; FSP27; CIDE-3
Gene ID: 63924
RefSeq ID-1: NP_001186480.1
RefSeq ID-2: NM_001199551.2
Summary: CIDEC is a member of the cell death-inducing DNA fragmentation factor-like effector family, which is involved in the regulation of apoptosis. In adipocytes, the encoded protein promotes lipid droplet expansion and influences fat storage capacity. Its expression is insulin-responsive and positively associated with insulin sensitivity, suggesting a role in metabolic homeostasis. Mutations in CIDEC may contribute to insulin resistance and metabolic disease.
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