Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
AdipoUpX™ Human CEBPA AAV Particle (Overexpression)
Cat. No.:
V1225XX342
Species:
Human
Target Gene:
CEBPA
Vector System:
AAV
Modulation Type:
Overexpression
SPECIFIC INQUIRY
Add to basket
| Sub Cat. No. | AAV Serotype | Tissue Tropism | Inquiry |
|---|---|---|---|
| V1225XX342-1 | AAV1 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX342-2 | AAV2 | CNS; Brain; Retina; Inner ear; Kidney; Testes; Liver; Pancreas; Smooth muscle | Inquiry |
| V1225XX342-3 | AAV3 | Lung; Liver; Smooth muscle | Inquiry |
| V1225XX342-4 | AAV4 | CNS; Retina; Heart; Lung; Kidney | Inquiry |
| V1225XX342-5 | AAV5 | CNS; Brain; Retina; Heart; Lung; Smooth muscle | Inquiry |
| V1225XX342-6 | AAV6 | Heart; Lung; Liver; Pancreas; Adipose; Smooth muscle | Inquiry |
| V1225XX342-7 | AAV7 | CNS; Brain; Retina; Liver; Smooth muscle | Inquiry |
| V1225XX342-8 | AAV8 | CNS; Brain; Retina; Inner ear; Heart; Liver; Pancreas; Kidney; Adipose; Smooth muscle | Inquiry |
| V1225XX342-9 | AAV9 | CNS; Brain; Retina; Inner ear; Heart; Lung; Liver; Pancreas; Kidney; Testes; Adipose; Skeletal muscle; Smooth muscle | Inquiry |
| V1225XX342-10 | Other | Inquiry |
Product Overview
Description:
AdipoUpX™ Human CEBPA AAV Particle (Overexpression) is a high-titer, ready-to-use AAV product and ensures the efficient and stable expression of the human CEBPA gene through an optimized promoter. Specifically designed for validating the role of this master transcription factor in adipocyte differentiation and insulin sensitivity, it serves as a reliable tool for metabolic signaling research. This product is supported by flexible reporter gene selection and comprehensive quality control screening to ensure experimental reliability.
Production Cell Line:
HEK293
AAV ITR:
AAV2 ITR
Promoter:
CMV (default); Other universal or cell-specific promoters
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Vector genome integrity for all preparations was successfully confirmed by PCR validation.
Sterility Test:
The QC assay verified the sterility of this product lot.
Mycoplasma Test:
The product was confirmed free of mycoplasma contamination after being subjected to stringent quality control testing.
Other QC:
Based on specific project requirements, we provide customized supplementary testing and conduct in vivo and in vitro transduction assessments to thoroughly analyze transgene expression levels and biological functions.
Storage:
Following receipt, immediate transfer to a -80°C is essential to maintain product integrity.
Stability:
Excellent stability for 6-12 months is guaranteed when the product is stored consistently at -80°C, a period which can extend up to 2 years. The thawed working solution is stable for 2-3 weeks at 4°C.
Shipping Condition:
Our AAV viral products are shipped using dry ice.
Handling Notes:
To maintain titer and prevent the damaging effects of repeated freeze-thaw cycles, it is recommended that the vector be aliquoted into low-protein-binding tubes immediately upon receipt; remember to perform all necessary operations inside a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes. While our company commits to product quality via rigorous internal QC inspections, we do not guarantee product performance or experimental results in any specific application due to diverse and complex conditions.
Target Profile
Gene Name:
CEBPA
Full Name:
CCAAT enhancer binding protein alpha
Gene Symbol:
CEBP; C/EBP-alpha
Gene ID:
1050
RefSeq ID-1:
NP_001272758.1
RefSeq ID-2:
NM_001285829.2
Summary:
The CEBPA gene produces a leucine zipper transcription factor that is a master regulator of body weight homeostasis and cell cycle control. By binding to CCAAT motifs in target promoters, it coordinates the differentiation of fat cells (adipocytes) and liver cells. Mutations in this gene are notably linked to acute myeloid leukemia, while its alternative translation into various isoforms allows it to fine-tune its regulatory impact on energy balance.
Related Products
-
AdipoUpX™ Human ACOT11 AAV Particle (Overexpression)
-
AdipoUpX™ Human CARTPT AAV Particle (Overexpression)
-
LipoKnoxa™ Human UCP1 shRNA AAV Particle (Silencing)
-
AdipoUpX™ Human PLIN1 AAV Particle (Overexpression)
-
LipoKnoxa™ Human SLC16A1 shRNA AAV Particle (Silencing)
-
AdipoUpX™ Human TBX3 AAV Particle (Overexpression)