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AC-55541
Cat. No.:
0225LY-1471
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
AC-55541 is a novel PAR2 agonist that stimulates cellular proliferation and calcium mobilization with potencies between 200 and 1000 nM.
Synonym:
AOB2796; 916170-19-9; AC 55541; AC55541; N-[2-[(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide; (E)-N-(2-(2-(1-(3-Bromophenyl)ethylidene)hydrazineyl)-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl)benzamide; (E)-N-(2-(2-(1-(3-Bromophenyl)ethylidene)hydrazinyl)-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl)benzamide; N-(2-((2E)-2-(1-(3-bromophenyl)ethylidene)hydrazinyl)-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl)benzamide
CAS No.:
916170-19-9
Compound CID:
9589606
Formula:
C25H20BrN5O3
Formula Weight:
518.36
Specification
Targets&IC50:
PAR2: 200-1000 nM(EC50)
Relative Density:
1.49 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
AC-55541 can be used in receptor biology to study the selective agonism of the PAR2 receptor and its role in inflammatory signaling.
Library Information
Target:
Proteasome; PAR
Receptor:
PAR; Protease-activated receptor 2
Pathways:
Proteases/Proteasome; Ubiquitination; GPCR/G protein signaling
Plate Number:
AOCL-19
Plate Location:
h4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
5.19 mg/mL; 10.01 mM
