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4-Octyl itaconate
Cat. No.:
0225LY-1443
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
4-Octyl Itaconate is a cell-permeable derivative of itaconate that exerts anti-inflammatory effects by activating Nrf2 via KEAP1 alkylation and blocking STING phosphorylation.
Synonym:
3133-16-2; 2-Methylene-4-(octyloxy)-4-oxobutanoic acid; 2-methylidene-4-(octyloxy)-4-oxobutanoic acid; Itaconic acid 4-octyl ester; 4-OctylItaconate; 2-methylidene-4-octoxy-4-oxobutanoic acid; 2-Methylene-4-octoxy-4-oxo-butanoic acid
CAS No.:
3133-16-2
Compound CID:
14239884
Formula:
C13H22O4
Formula Weight:
242.31
Specification
Relative Density:
1.026 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
4-Octyl itaconate can be used in immunology research to study the anti-inflammatory mechanisms of endogenous metabolites in macrophage activation.
Library Information
Target:
Nrf2
Receptor:
Keap1-Nrf2 Interface
Pathways:
Oxidative stress; Immunology/Inflammation; Chromatin/Epigenetic
Plate Number:
AOCL-19
Plate Location:
e6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
237.5 mg/mL; 980.15 mM
