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Tetrabenazine
Cat. No.:
0225LY-1330
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Tetrabenazine is a medication formerly used as an antipsychotic for movement disorders; it works by labeling the vesicle transport system and preventing neurotransmitter uptake into storage vesicles.
Synonym:
Xenazine; Ro 1-9569; 58-46-8; Nitoman; Rubigen; Tetrabenazine racemate; Tetrabenzine; Tetrabenazinum; Tetrabenazine (Racemate); 3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one; 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one; 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one; Deutetrabenazine; 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
CAS No.:
58-46-8
Compound CID:
6018
Formula:
C19H27NO3
Formula Weight:
317.42
Specification
Relative Density:
1.12 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Tetrabenazine can be used in neuroscience to study the inhibition of the vesicular monoamine transporter 2 (VMAT2) and its impact on dopamine depletion.
Library Information
Target:
Dopamine receptor; Monoamine Transporter
Receptor:
D2 receptor; VMAT
Pathways:
Neuronal signaling; GPCR/G protein signaling; Membrane transporter/Ion channel
Plate Number:
AOCL-18
Plate Location:
a7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
18.33 mg/mL; 57.75 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
32 mg/mL; 100.81 mM
