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RSVA405
Cat. No.:
0225LY-0532
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
RSVA405 acts as both an AMPK activator (EC50 = 1 μM) and a STAT3 inhibitor.
Synonym:
RSVA 405; 140405-36-3; 2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylicacid; N'-(4-(Diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide; N-[(E)-[4-(Diethylamino)-2-hydroxy-phenyl]methyleneamino]pyridine-4-carboxamide
CAS No.:
140405-36-3
Compound CID:
135400298
Formula:
C17H20N4O2
Formula Weight:
312.37
Specification
Targets&IC50:
AMPK: 1 μM(EC50)
Relative Density:
1.16 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
RSVA405 can be used in protein homeostasis research to investigate the activation of AMPK and its role in proteasomal degradation.
Library Information
Target:
STAT; AMPK
Receptor:
AMPK; STAT3
Pathways:
Chromatin/Epigenetic; Autophagy; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem cell regulation
Plate Number:
AOCL-7
Plate Location:
h6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
25 mg/mL; 80.03 mM
