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Rosiglitazone
Cat. No.:
OB0225LY-0365
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Rosiglitazone is a thiazolidinedione drug that acts primarily as an insulin sensitizer and is able to regulate metabolic processes.
Synonym:
BRL49653; 122320-73-4; Avandia; Rosiglizole; 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-; 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-; 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
CAS No.:
122320-73-4
Compound CID:
77999
Formula:
C18H19N3O3S
Formula Weight:
357.43
Specification
Relative Density:
1.315 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Rosiglitazone can be used in diabetes research or play an important role in metabolic syndrome modeling.
Library Information
Targets:
PPAR family; TRP/TRPV channel
Receptors:
PPARγ; TRPC5; TRPM3
Pathways:
Apoptosis; DNA damage/DNA repair; Membrane transporter/Ion channel; Autophagy; Metabolism
Plate Number:
AOCL-5
Plate Location:
f10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
45 mg/mL; 125.9 mM
Special Max Solubility:
1eq. HCl: 35.7 mg/mL
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.57 mg/mL (9.99 mM)
ALogP:
3.268
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
7
