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Vitamin B12 test kit

Phloretin

Cat. No.: 0225LY-1413
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and LC-MS.
Size:
Phloretin
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Product Overview

Description: Phloretin is a natural dihydrochalcone found in Manchurian apricot and apple leaves that inhibits eukaryotic urea transporters and VacA-mediated transport; it is a strong scavenger of peroxynitrite that prevents lipid peroxidation and can induce apoptosis in certain leukemia and melanoma cell lines.
Synonym: Dihydronaringenin; NSC 407292; RJC 02792; 60-82-2; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one; Dihydronaringenin; Phloretol; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone; 1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-; Beta-(p-Hydroxyphenyl)phloropropiophenone; 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone; 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone; NSC407292; Beta-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone; beta-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone; 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)-propiophenone; Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-
CAS No.: 60-82-2
Compound CID: 4788
Formula: C15H14O5
Formula Weight: 274.27

Specification

Relative Density: 1.429 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Phloretin can be used in metabolic studies to investigate the inhibition of glucose transporters and its impact on cellular energy uptake.

Library Information

Target: SGLT; Glucose transporter
Receptor: GLUT; SGLT1; SGLT2
Pathways: Metabolism; GPCR/G protein signaling
Plate Number: AOCL-19
Plate Location: b6
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 80 mg/mL; 291.68 mM
Water Max Solubility: <1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility: 48 mg/mL; 175.01 mM
ALogP: 2.757
HBA_Count: 1
HBD_Count: 4
Rotatable Bond: 4
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