LipoKnoxa™ Human SLC27A4 shRNA Ad5 Particle (Silencing)

Cat. No.: V0126XX158

Species: Human

Target Gene: SLC27A4

Vector System: Adenovirus

Modulation Type: Silencing (shRNA)

LipoKnoxa™ Human SLC27A4 shRNA Ad5 Particle (Silencing)

INQUIRY Datasheet MSDS

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX158-1	AGAGAGCAGGGAGCTTATAAA	3' UTR	Inquiry
V0126XX158-2	GTGGTGCACAGCAGGTATTAC	CDS	Inquiry
V0126XX158-3	CCTTGTCTTTGGCAGCGAAAT	CDS	Inquiry
V0126XX158-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human SLC27A4 shRNA Ad5 Particle (Silencing) targets FATP4, a major facilitator of long-chain fatty acid uptake in the intestine and adipose tissue. Utilizing high-efficiency Ad5 delivery of optimized shRNA (supporting U6 or miR30 systems), researchers can investigate the rate-limiting steps of lipid absorption. Every batch is subjected to comprehensive quality control, including validated functional titers and sterility testing, to deliver consistent results in nutrient transport research.

Production Cell Line: HEK293

Viral Backbone: Adenovirus type 5 (dE1/E3)

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: All viral preparations are validated via Sequencing and PCR to ensure 100% sequence identity and the structural integrity of the vector genomes.

Sterility Test: This product has been certified sterile following comprehensive microbial growth analysis, confirming the absence of bacterial and fungal contamination.

Mycoplasma Test: This product was certified negative for mycoplasma contamination following stringent QC analysis, ensuring the absence of all mycoplasmal agents.

Other QC: Beyond standard protocols, we offer customized knockdown efficiency validation through in vitro and in vivo assessments. This includes precise analysis of mRNA/protein reduction and subsequent biological responses to ensure the functional potency of the shRNA-mediated gene silencing.

Storage: Upon receipt, viral preparations should be immediately transferred to -80°C for long-term storage to ensure maximum stability and maintain product integrity.

Stability: This product maintains excellent biological activity for 6–12 months (and up to 2 years in specific cases) when stored continuously at -80°C. Once thawed, the working solution remains stable for 2–3 weeks at 4°C without significant loss of viral potency.

Shipping Condition: All viral preparations are shipped on dry ice to ensure maximum biological activity and stability during transit.

Handling Notes: Viral particles are susceptible to temperature fluctuations and freeze-thaw cycles. To preserve functional titers, it is essential to aliquot the vector into low-protein-binding tubes immediately upon first thaw. To ensure experimental success and biological safety, all procedures must be conducted within a certified biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: While our products are committed to excellence through rigorous internal QC inspections, we cannot guarantee specific performance or experimental outcomes due to the inherent complexity of biological systems. Users assume full responsibility for product storage, handling, and strict compliance with all applicable safety protocols, biosafety requirements, and legal regulations during all operational processes.

Target Profile

Gene Name: SLC27A4

Full Name: Solute carrier family 27 member 4

Gene Symbol: IPS; FATP4; ACSVL4

Gene ID: 10999

RefSeq ID-1: NP_005085.2

RefSeq ID-2: NM_005094.3

Summary: SLC27A4 (FATP4) is the principal fatty acid transporter in the small intestine. Facilitating the absorption of dietary long-chain fatty acids, it determines the entry of lipids into systemic circulation. Clinical research identifies it as a candidate gene for insulin resistance syndrome, as its transport efficiency directly impacts postprandial lipid levels.

Related Products

Inquiry

Inquiry Basket

Delete selected Check Out