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Linetastine
Cat. No.:
OB0225LY-0124
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
Linetastine is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.
Synonym:
TMK 688; TMK-688; TMK688; 159776-68-8; Linazolast; [4-[(1E-,3E)-5-[2-(4-Benzhydryloxypiperidin-1-yl)ethylamino]-5-oxopenta-1,3-dienyl]-2-methoxyphenyl] ethyl carbonate; (2E,4E)-N-(2-(4-(Diphenylmethoxy)piperidino)ethyl)-5-(4-hydroxy-3-methoxyphenyl)-2,4-pentadienamide ethyl carbonate (ester); 1-((5'-(3''-Methoxy-4''-ethoxycarbonyloxyphenyl)-2',4'-pentadienoyl)aminoethyl)-4-diphenylmethoxypiperidine
CAS No.:
159776-68-8
Compound CID:
6439232
Formula:
C35H40N2O6
Formula Weight:
584.7
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Linetastine can be used to study allergic reactions such as allergic rhinitis and urticaria.
Library Information
Targets:
Histamine receptor; LTR; Lipoxygenase family
Receptors:
5-LOX
Pathways:
Immunology/Inflammation; Neuronal signaling; Metabolism; GPCR/G protein
Plate Number:
AOCL-2
Plate Location:
e7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 85.51 mM
