Human necdin ELISA kit (0.312-20 ng/mL)

Cat. No.: 0126WXX-1063

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: Necdin

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INQUIRY Datasheet MSDS

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Product Overview

Description: Human necdin ELISA kit (0.312-20 ng/mL, 0.1 ng/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of necdin in human samples with a range of 0.312-20 ng/mL and a minimum detectable dose (sensitivity) of 0.1 ng/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on necdin antibody-necdin antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect necdin antigen targets in samples.

Background: Necdin is a protein located within neuronal cell nuclei and is considered a transcriptional repressor. It belongs to the genes within the critical region of Prader-Willi syndrome (PWS). PWS is a genetic disorder characterized by severe morbid obesity and hyperphagia, primarily attributed to the deletion or dysfunction of genes within the PWS region (including Necdin). This suggests Necdin participates in the normal suppression of satiety and food intake within the hypothalamus.

Synonyms: NDN

Applications: Human necdin ELISA kit (0.312-20 ng/mL, 0.1 ng/mL) is used to quantify necdin in serum, plasma, whole blood, tissue, saliva, urine, feces, and other fluids of human, providing data to support research in a wide range of areas, including appetite regulation, signal transduction, obesity, etc.

Research Area: Appetite regulation; Signal transduction; Obesity