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Duloxetine hydrochloride
Cat. No.:
0225LY-0637
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Duloxetine hydrochloride is a thiophene-based SNRI (serotonin and noradrenaline reuptake inhibitor) used as an antidepressant and anxiolytic, as well as for managing pain associated with fibromyalgia and diabetes.
Synonym:
Duloxetine HCl; (S)-Duloxetine hydrochloride; 136434-34-9; Cymbalta; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride; Ariclaim; Duloxetine mylan; (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride; (+)-(S)-N-Methyl-gamma-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride; Methyl[3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine hydrochloride; 2-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, hydrochloride, (gammaS)-; (S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine monohydrochloride
CAS No.:
136434-34-9
Compound CID:
60834
Formula:
C18H20ClNOS
Formula Weight:
333.88
Specification
Targets&IC50:
SNRI: 4.6 nM(Ki)
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Duloxetine hydrochloride can be used in pharmacology to investigate the dual reuptake inhibition of serotonin and norepinephrine.
Library Information
Target:
SERT; DAT; NET; 5-HTR; DAR
Receptor:
DAT; NET; SERT
Pathways:
Neuronal signaling; GPCR/G protein signaling
Plate Number:
AOCL-9
Plate Location:
c3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 748.77 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
