Amitriptyline hydrochloride

Cat. No.: OB0225LY-0099

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR and HPLC.

Size:

INQUIRY Datasheet MSDS

Product Overview

Description: Amitriptyline hydrochloride is a tricyclic antidepressant with antidepressant activity. Its salt form of hydrochloride enhances the solubility of the drug.

Synonym: Amitriptyline HCl; Tryptizol; Domical; Annoyltin; 549-18-8; 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene; 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N, N-dimethyl-1-propanamine; 10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene; 3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N, N-dimethylpropan-1-amine; 5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene; 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N, N-dimethylpropylamin; 5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N, N-dimethyl-

CAS No.: 549-18-8

Compound CID: 2160

Formula: C₂₀H₂₄ClN

Formula Weight: 313.86

Specification

Relative Density: 1.23 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Amitriptyline hydrochloride can be used in the management of neuropathic pain, migraine prevention, and anxiety disorders, among others.

Library Information

Targets: Monoamine transporters; G protein-coupled receptors (GPCRs); Neurotrophin receptors; Ion channels

Receptors: 5-HT receptor; mAChR; Norepinephrine receptor; Serotonin transporter; Sodium channel; Trk receptor; σ1; Histamine receptor; Adrenergic receptor

Pathways: Membrane transporter/Ion channel; Tyrosine kinase/adaptors; Immunology/Inflammation; GPCR/G protein; Neuronal signaling

Plate Number: AOCL-2

Plate Location: c2

Empty Location: a1-h1; a12-h12

Container: 96-well plate

Formulation: 10 mM DMSO

DMSO Max Solubility: 50 mg/mL; 159.31 mM

Water Max Solubility: 12 mg/mL; 38.2 mM

Ethanol Max Solubility: 59 mg/mL; 188 mM