AdipoUpX™ Human SLC2A4 Ad5 Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human SLC2A4 Ad5 Adenoviral Particle (Overexpression) is a ready-to-use Ad5 adenovirus vector particle designed for the transient overexpression of the human SLC2A4 (GLUT4) gene. It enables researchers to investigate the insulin-responsive glucose transporter and its role in improving glucose clearance in muscle and fat cells. The product’s integrity is guaranteed by rigorous purification and comprehensive QC screening.

Production Cell Line: HEK293

Viral Backbone: Adenovirus type5 (dE1/E3)

Promoter: CMV

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: All viral preparations have been validated via PCR to confirm the integrity of their vector genomes.

Sterility Test: This product was confirmed to be sterile upon testing.

Mycoplasma Test: This product has passed quality control, confirming that it is free of mycoplasma contamination.

Other QC: We perform customized supplementary testing and in vitro/in vivo transduction assessments based on specific project requirements to analyze the expression levels and biological functions of transgenes.

Storage: Upon receipt of viral preparations, they must be immediately transferred to a -80°C environment for long-term storage.

Stability: The product guarantees excellent stability for 6-12 months when stored continuously at -80°C (and in some cases, up to 2 years). Upon thawing, the working solution is refrigerated at 4°C for up to 2-3 weeks without significant loss of biological activity.

Shipping Condition: Our adenovirus viral products are shipped using dry ice.

Handling Notes: Viral particles are highly sensitive to temperature fluctuations and freeze-thaw cycles. To maintain titer and avoid repeated freeze-thaw cycles, it is recommended to aliquot the vector immediately upon receipt into low-protein-binding tubes and store according to specified conditions. Ensure all operations are performed within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Our company is committed to product quality, and all products have undergone rigorous internal QC inspections. Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application. Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes.

Target Profile

Gene Name: SLC2A4

Full Name: Solute carrier family 2 member 4

Gene Symbol: GLUT4

Gene ID: 6517

RefSeq ID-1: NP_001033.1

RefSeq ID-2: NM_001042.3

Summary: SLC2A4 encodes GLUT4, the insulin-regulated glucose transporter. In a resting state, this protein is sequestered in intracellular vesicles in muscle and fat cells. However, within minutes of an insulin signal, GLUT4 moves to the cell surface to transport glucose from the blood into the cell. This rapid translocation is the primary mechanism for lowering blood sugar after eating. Mutations in this gene or defects in its movement to the membrane are major drivers of insulin resistance and non-insulin-dependent diabetes.

AdipoUpX™ Human SLC2A4 Ad5 Particle (Overexpression)

Product Overview

Specification

Target Profile

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