AdipoUpX™ Human MYT1L Ad5 Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MYT1L Ad5 Adenoviral Particle (Overexpression) utilizes a highly efficient promoter for the overexpression of the human MYT1L gene. This transcription factor is essential for neuronal differentiation and is linked to syndromic obesity and intellectual disability. This product serves as a powerful tool for neuro-metabolic research, supported by flexible reporter gene inclusion and full QC testing.

Production Cell Line: HEK293

Viral Backbone: Adenovirus type5 (dE1/E3)

Promoter: CMV

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: All viral preparations have been validated via PCR to confirm the integrity of their vector genomes.

Sterility Test: This product was confirmed to be sterile upon testing.

Mycoplasma Test: This product has passed quality control, confirming that it is free of mycoplasma contamination.

Other QC: We perform customized supplementary testing and in vitro/in vivo transduction assessments based on specific project requirements to analyze the expression levels and biological functions of transgenes.

Storage: Upon receipt of viral preparations, they must be immediately transferred to a -80°C environment for long-term storage.

Stability: The product guarantees excellent stability for 6-12 months when stored continuously at -80°C (and in some cases, up to 2 years). Upon thawing, the working solution is refrigerated at 4°C for up to 2-3 weeks without significant loss of biological activity.

Shipping Condition: Our adenovirus viral products are shipped using dry ice.

Handling Notes: Viral particles are highly sensitive to temperature fluctuations and freeze-thaw cycles. To maintain titer and avoid repeated freeze-thaw cycles, it is recommended to aliquot the vector immediately upon receipt into low-protein-binding tubes and store according to specified conditions. Ensure all operations are performed within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Our company is committed to product quality, and all products have undergone rigorous internal QC inspections. Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application. Users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements throughout all operational processes.

Target Profile

Gene Name: MYT1L

Full Name: Myelin transcription factor 1 like

Gene Symbol: NZF1; MRD39; myT1-L; ZC2H2C2; ZC2HC4B

Gene ID: 23040

RefSeq ID-1: NP_001289981.1

RefSeq ID-2: NM_001303052.2

Summary: MYT1L encodes a zinc finger transcription factor that is essential for the development and identity of neurons in the central nervous system. It is so powerful that it can reprogram fibroblasts into functional neuronal cells. Current clinical evidence demonstrates that MYT1L variants are significantly associated with syndromic obesity in humans, alongside cognitive disabilities and autism spectrum disorders. This highlights MYT1L as a master regulator of the neurodevelopmental pathways that govern metabolic control and satiety.

AdipoUpX™ Human MYT1L Ad5 Particle (Overexpression)

Product Overview

Specification

Target Profile

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