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AdipoUpX™ Human CD36 MMLV Particle (Overexpression)
Cat. No.:
V1225XX712
Species:
Human
Target Gene:
CD36
Vector System:
MMLV Retrovirus
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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Product Overview
Description:
AdipoUpX™ Human CD36 MMLV Particle (Overexpression) is a high-titer, ready-to-use MMLV retroviral particle professionally engineered for the stable overexpression of the human CD36 gene. As a multifunctional scavenger receptor, it is essential for researching long-chain fatty acid uptake and lipid-induced inflammation. The MMLV vector stably integrates into the genome of dividing host cells, making it an ideal tool for establishing stable cell lines. Our modular system allows for high flexibility in customization, and all products pass comprehensive quality control.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.
Sterility Test:
The final viral preparation was confirmed sterile after testing.
Mycoplasma Test:
Mycoplasma contamination testing met all release specifications for all product lots.
Other QC:
We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.
Storage:
The product must be immediately transferred to -80 °C storage upon its arrival.
Stability:
For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.
Shipping Condition:
Our MMLV retroviral products are shipped using dry ice.
Handling Notes:
Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.
Target Profile
Gene Name:
CD36
Full Name:
CD36 molecule (CD36 blood group)
Gene Symbol:
FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10
Gene ID:
948
RefSeq ID-1:
NP_000063.2
RefSeq ID-2:
NM_000072.3
Summary:
CD36 encodes a versatile scavenger receptor that facilitates the transport of long-chain fatty acids into cells. Beyond its metabolic role, it serves as a receptor for thrombospondin, collagen, and oxidized LDL, playing a significant part in cell adhesion and inflammatory signaling. Its ability to regulate lipid uptake makes it a key candidate gene for studies on fat accumulation and atherosclerosis.