AdipoUpX™ Human ACSL1 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ACSL1 MMLV Particle (Overexpression) is a ready-to-use retroviral vector particle professionally engineered for the stable overexpression of the human ACSL1 gene. It is a key isoform for activating long-chain fatty acids for both oxidation and lipid synthesis in the heart and adipose tissues. Because the MMLV particle integrates into the dividing cell genome, it is perfect for establishing stable metabolic cell lines for flux analysis. Comprehensive quality control ensures the safety and efficacy of all viral products, providing a robust tool for energy homeostasis research.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: ACSL1

Full Name: Acyl-CoA synthetase long chain family member 1

Gene Symbol: ACS1; LACS; FACL1; FACL2; LACS1; LACS2

Gene ID: 2180

RefSeq ID-1: NP_001273637.1

RefSeq ID-2: NM_001286708.2

Summary: ACSL1 is a member of the ligase family that "primes" long-chain fatty acids by converting them into fatty acyl-CoA esters. This activation is the mandatory first step for either burning fat for energy or building it into complex lipids, making it a central regulator of metabolic flux.

AdipoUpX™ Human ACSL1 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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