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Obesity-related Metabolic Assay Kit

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Unlocking Metabolic Insights: Your Comprehensive Obesity-related Assay Kit

Many tissues and organs in obese individuals exhibit dysregulation of mitochondrial function, lipid metabolism, and glucose uptake. Given this, obesity-related metabolic assays are highly desirable. Obesity-related metabolic assay kits are laboratory tools specifically designed to measure and analyze metabolic functions associated with obesity and metabolic diseases. These kits help researchers to assess glucose uptake, lipid metabolism, and other parameters in a variety of biological samples. Protheragen is committed to providing users with the highest quality products and services based on our deep expertise in the field of obesity. Our obesity-related metabolic assay kits are not only comprehensive, accurate, and easy to use, but also highly flexible and scalable to meet the diverse needs of users.

Link between metabolic syndrome and adipocyte biology. (Attie & Scherer, 2009)

Our kits cover detecting a range of key metabolic indicators, providing researchers with a comprehensive and accurate tool for the metabolic assessment of obesity. Testing options include lipid metabolism-related indicators (cholesterol, triglycerides, free fatty acids, etc.), glycolysis-related indicators (glucose, etc.), urea metabolism-related indicators (urea, etc.), and more. The appropriate kits are chosen by researchers according to their specific research needs. Meanwhile, these kits also support various sample types, such as cell lysates, biofluid samples, etc. Through the use of these kits, researchers deeply investigate the changes in metabolic pathways, the pathogenesis of obesity, and its related metabolic diseases, and provide a scientific basis for the development of effective therapeutic strategies.

Applications

Obesity research: These kits are used to detect various metabolic-related indicators to investigate the pathophysiological mechanisms of obesity and metabolic disorders, thus providing a scientific basis for the development of effective therapeutic strategies.
Drug discovery: These kits also play an important role in anti-obesity drug discovery and treatment evaluation. By analyzing the impact of drugs on metabolic pathways, researchers can evaluate both the safety and effectiveness of medications, offering robust support for the continued refinement of anti-obesity therapies.
Nutritional intervention studies: These kits are widely used to measure the effects of various dietary and lifestyle modifications on metabolic indicators, providing valuable data for in-depth analysis of weight loss strategies.

Advantages

(Protheragen)

Comprehensive: Designed for obesity and its related metabolic diseases, our metabolic test kits can accurately detect obesity-related metabolic indicators, such as lipid metabolism, glucose metabolism, etc., thus providing targeted test results.
Stable and reliable data: These kits are manufactured in strict accordance with quality control standards to ensure the stability and reliability of the test results, allowing researchers to analyze and interpret the data accurately.
High sensitivity and specificity: These kits enable accurate detection of metabolic markers at low concentrations, and the assays are usually completed in a short period of time, which greatly improves research efficiency.

Publication

The obesity-related metabolic assay kit covers a wide range of assay types. These assays help to comprehensively assess the metabolic status and provide a scientific basis for evaluating anti-obesity drugs. In this study, researchers used a triglyceride colorimetric assay kit to measure triglycerides in the liver and performed other metabolic assays and histological analyses to analyze the role of a drug targeting the farnesoid X receptor (FXR) in ameliorating obesity-associated metabolic dysfunction. The results showed that glycine-β-muricholic acid (Gly-MCA), a selective and high-affinity FXR inhibitor, could improve metabolic disorders and had a role in preventing or reversing genetic obesity, insulin resistance, and hepatic steatosis induced by a high-fat diet in mice.

Fig.1 reversal of metabolic dysfunction by Gly-MCA. Fig.1 Metabolic function analysis of obese mice. (Jiang, et al., 2015)

This study demonstrates the role of metabolic assay kits in anti-obesity research and provides an effective strategy for anti-obesity drug development.

Frequently Asked Questions

What types of samples can the metabolic assay kits be used for?
These kits are versatile and used for a variety of sample types, including
- Cell lines: e.g., adipocytes, hepatocytes.
- Primary cells: Isolated from human or animal tissue.
- Tissue samples: Tissue samples such as liver and adipose tissue.
- Blood samples: Serum or plasma used to measure metabolic markers.
- Other types of samples
How do I choose the right assay kit for my research?
You can consider the following points when choosing an assay kit:
- Research objective: Identify the specific metabolic pathway or biomarker you want to study.
- Sample type and availability: Make sure the kit is compatible with your sample type and has sufficient sample volume.
- Sensitivity and specificity: Select a kit with an appropriate detection limit based on the expected analyte concentration.
- Assay format: Select the assay method according to the experimental situation, including colorimetric, fluorescent, and other detection methods.

Protheragen works with you to advance research into obesity and its treatment. Our obesity-related metabolic assay kits are ideal for your obesity metabolic assessment. Please do not hesitate to contact us with any questions or requests, and we will be happy to assist you.

Referencess

Jiang, C.; et al. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nature Communications. 2015, 6(1): 10166. (CC BY 4.0)
Attie, A.D.; Scherer, P.E. Adipocyte metabolism and obesity. Journal of Lipid Research. 2009, 50: S395-S399. (CC BY 4.0)

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