Overview of Monkey Obesity Model

Protheragen is dedicated to providing comprehensive solutions for life science research and drug development. We are proud to launch the monkey obesity model development service as an important part of our Preclinical Studies of Anti-Obesity Therapeutics, which aims to help researchers explore the mechanism of obesity and evaluate the efficacy of anti-obesity drugs.

Our services cover a wide range of Obesity Models, especially In Vivo Obesity Models for Obesity Research, where we provide highly customized non-human primate obesity model construction and evaluation services. This service not only simulates the complex physiological and pathological processes of human obesity but also greatly improves the success rate of clinical translation of experimental results.

We utilize our monkey obesity model as a vital platform for evaluating and facilitating Anti-Obesity Therapy Development. This model, due to its close phylogenetic relationship to humans, offers unique insights into the efficacy and safety of Anti-Obesity Cell Therapy Development and Anti-Obesity Antibody Therapy Development. By replicating human obesity-related conditions, it enables us to rigorously test and refine our therapeutic candidates, paving the way for more effective and safer anti-obesity treatments to enter clinical trials.

Comprehensive Monkey Obesity Model Development Service for Cutting-Edge Research and Precise Metabolic Insights

We mainly use rhesus macaque as the experimental subject for constructing obesity models because it has high similarities with humans in genetics, physiology, and metabolic characteristics and is an ideal non-human primate experimental animal.

• Obesity Model Construction

  • Feed Management

    High-Sugar and High-Fat feed: Rhesus monkeys are fed with scientifically formulated high-sugar and high-fat feed for a long time to simulate human obesity caused by changes in dietary structure. Adjust feed formula and intake according to weight gain.

  • Environmental Control

    We provide a suitable breeding environment, including temperature, humidity, light cycle, etc., to reduce the impact of external factors on experimental results.

    We regularly monitor the health of animals to ensure that the welfare of animals is guaranteed during the experiment.

  • Evaluation Indicators

    Weight-to-body fat ratio: Weigh regularly and use imaging technology to evaluate body fat distribution.

    Biochemical indicators: Detect biochemical indicators such as blood sugar, blood lipids, and insulin in serum to evaluate metabolic status.

    Behavioral observation: Record the activity level, eating behavior, etc., of animals to evaluate the impact of obesity on behavior.

• Obesity Model Evaluation

  Drug intervention experiment: After the model is successfully constructed, the experimental monkeys are intervened with anti-obesity drugs to observe and record weight changes, improvements in biochemical indicators, and drug side effects.

  Histopathological analysis: We take some tissue samples for pathological examination to evaluate the effects of obesity and drug intervention on organ structure.

  Molecular biology analysis: We use molecular biology techniques to detect changes in gene expression related to obesity and further explore the mechanism of obesity.

Workflow

Applications of Monkey Obesity Model

• Drug development: This model can be used to evaluate the efficacy and safety of potential anti-obesity drugs.
• Disease mechanism research: This model can be used to further study the pathogenesis of obesity and its related complications.
• Nutritional research: This model can be used to conduct nutritional intervention experiments to evaluate the effects of different dietary patterns on the occurrence and development of obesity, and provide a basis for the formulation of scientific and reasonable dietary guidelines.

Advantages

• Highly simulated human physiology: Our monkey obesity model has highly similar physiological and genetic characteristics to humans, and can more accurately simulate the pathogenesis of human obesity and related diseases.
• Customized service: We tailor experimental plans according to client needs to ensure the accuracy and reliability of experimental results.
• One-stop solution: We provide a one-stop solution from model maintenance to results transformation to help clients achieve rapid transformation and application of research results.

Publication

Our Services

Frequently Asked Questions

What are the advantages of the monkey obesity model compared with other animal models?

Compared with other animal models such as mice and rats, the monkey obesity model has higher physiological and genetic similarities with humans, so it can more accurately simulate the pathogenesis and drug response of human obesity and related diseases. This makes the model unique in the fields of drug development, disease mechanism research, and personalized medicine.

How to evaluate the research value and application prospects of the monkey obesity model?

• Monkey obesity model can provide more accurate disease simulation and drug response prediction, and accelerate the development and listing of new drugs.
• The monkey obesity model helps to explore the pathogenesis of obesity and related diseases in depth and provides a theoretical basis for disease prevention and treatment.
• The monkey obesity model can be applied in the field of personalized medicine to provide accurate treatment plans for obese patients.

With the continuous development of biotechnology, the value of the monkey obesity model in biomedical research will become more and more prominent.

Protheragen focuses on providing a monkey obesity model development service. We use cutting-edge biotechnology to accurately construct monkey models that highly simulate the pathophysiological changes of human obesity, providing a reliable and efficient experimental platform for drug development, disease mechanism exploration, and personalized medicine. Please feel free to contact us for more details if you are interested in our monkey obesity model development services!

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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