Obesity Biomarker Identification and Analysis Service

Leptin Analysis Service

Leptin, produced by the obese gene, is a hormone that regulates food intake, body mass, and reproductive functions. Additionally, it plays a crucial role in fetal development, immune system responses, blood vessel formation, and the breakdown of fats. By utilizing our leptin analysis service, you gain access to comprehensive data on leptin levels, enhancing your understanding of its role in obesity and related metabolic disturbances.

Adiponectin Analysis Service

We provide the precise evaluation of adiponectin, a pivotal peptide hormone synthesized by adipocytes. As the predominant peptide within adipose tissue, adiponectin is integral to maintaining metabolic balance. Diminished levels of adiponectin are strongly correlated with a range of obesity-related pathologies, such as insulin resistance, type 2 diabetes, and cardiovascular disorders.

Adipocyte Fatty Acid–binding Protein Analysis Service

Our research team measures the circulating adipocyte-derived fatty acid-binding protein, a key biomarker associated with obesity and metabolic syndrome. By assessing serum adipocyte-derived fatty acid-binding protein concentrations, we provide critical insights into metabolic and cardiovascular conditions associated with obesity. Elevated levels of adipocyte-derived fatty acid-binding protein are frequently indicative of an increased risk for these health complications, underscoring the significance of its measurement for clinical diagnosis and risk stratification.

Inflammatory Cytokine Analysis Service

Our researchers conduct the identification and analysis of inflammatory cytokines associated with obesity. In the context of obesity, macrophages in adipose tissue commonly transition to a pro-inflammatory M1 phenotype, releasing cytokines that impair insulin signaling and aggravate insulin resistance. By measuring these cytokines in serum or tissue samples, our analysis delivers profound insights into the inflammatory pathways that underpin obesity.

Resistin Analysis Service

Our researchers use their professional knowledge to quantify resistin levels in serum to explore its role in obesity. Predominantly expressed in white adipocytes and blood cells, resistin operates through a paracrine mechanism, counteracting insulin effects and diminishing glucose uptake in adipocytes, muscle cells, and other tissues. Our service facilitates a deeper understanding of resistin's functions, aiding in the early diagnosis and personalized treatment of obesity and related metabolic disorders.

Endocannabinoid Analysis Service

With advanced technologies, we assess endocannabinoid levels as biomarkers for obesity and related metabolic disorders. The endocannabinoid system plays a pivotal role in managing energy balance and is a promising target for therapeutic strategies aimed at obesity. We offer precise measurements of circulating endocannabinoids in various biological fluids, including plasma, serum, cerebrospinal fluid, and saliva.

Platelet Analysis Service

We conduct a comprehensive evaluation of platelet activity and characteristics, with a specific focus on the implications of obesity. Platelets, essential for hemostatic and thrombotic responses, promptly aggregate at sites of vascular damage to prevent hemorrhage. Their role has become increasingly pivotal in various pathological conditions. In the case of obesity, metabolic disturbances induce alterations in bone marrow homeostasis, such as the expansion of bone marrow adipose tissue (BMAT) and an increased propensity for platelet hyperactivation due to multifaceted disruptions. Our service is dedicated to delivering precise assessments of platelet counts and activation, providing essential insights into how these parameters are modified in obesity and their broader implications for cardiovascular health.

Plasma Ceruloplasmin Analysis Service

We have many years of experience in assessing ceruloplasmin levels in the blood of obese individuals. The service identifies and evaluates ceruloplasmin, a crucial copper carrier and angiogenesis promoter, specifically detected in the adipose tissue of obese patients. By evaluating these levels, the service aims to uncover potential links between ceruloplasmin overexpression and obesity.

Cholesterol Analysis Service

We meticulously assess critical cholesterol metrics, including total cholesterol, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), to unravel their interplay with obesity and its associated health implications. Total cholesterol provides a comprehensive snapshot of overall cholesterol levels. In contrast, HDL-C, frequently referred to as "good" cholesterol, plays a vital role in clearing excess cholesterol from the bloodstream. LDL-C, known as "bad" cholesterol, contributes to the formation of arterial plaque. This detailed analysis is instrumental in elucidating the impact of obesity on cardiovascular health.

Triglyceride Analysis Service

We measure triglyceride levels in the blood, which are critical for understanding fat metabolism and associated cardiovascular risks. Triglycerides, the most common type of fat in the bloodstream, consist of three fatty acid chains linked by glycerol. Elevated levels of fasting plasma triglycerides are often linked with obesity and heighten the risk of heart disease and other cardiovascular conditions. By analyzing these triglyceride levels, the service provides valuable insights into how obesity impacts metabolic health.

Visfatin Analysis Service

Our researchers explore the identification and quantification of visfatin, a pivotal adipocytokine released from visceral fat and other tissues. This biomarker is instrumental in modulating both glucose and lipid metabolism. Elevated concentrations of visfatin are frequently linked with obesity, providing critical insights into the metabolic disruptions associated with excessive adiposity. Such analysis elucidates the impact of visfatin on insulin resistance, glucose regulation, and lipid profiles.

Insulin-Like Growth Factor (IGF) Analysis Service

We offer a comprehensive analysis of the IGF, a crucial component of normal metabolic regulation and its interaction with various hormonal pathways. In obesity, the resultant hyperinsulinemia from peripheral insulin resistance often leads to a decrease in growth hormone (GH) secretion. Despite this, total IGF-I levels generally remain constant due to increased hepatic sensitivity to GH. Our analysis sheds light on the involvement of the IGF system in obesity-associated vascular and other complications. By evaluating IGF levels, we identify disruptions in metabolic and endocrine equilibrium, thus providing essential data for crafting targeted therapeutic approaches to effectively manage obesity-related health challenges.

Oxidative Stress Biomarker Analysis Service

Our research team help clients to evaluate oxidative stress levels and their impact on obesity. Our service researches how oxidative stress contributes to the development of obesity and associated complications, explores the impact of dysfunctional adipose tissue, and studies the underlying causes of obesity. By analyzing oxidative stress markers and their effects, our service aims to offer valuable information for understanding and managing obesity more effectively.

DNA Methylation Analysis Service

We utilize DNA methylation patterns to pinpoint and elucidate biomarkers associated with obesity through our methylation analysis. DNA methylation, characterized by its dynamic and reversible properties, effectively mirrors environmental exposures and facilitates the prediction of obesity-related risks and developments. Compared to other biological markers, methylation patterns offer greater stability and ease of measurement. Existing predictors based on DNA methylation for obesity demonstrate significant potential.