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Croconazole
Cat. No.:
0225LY-0791
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Croconazole is an antimycotic agent that demonstrates inhibitory activity on neutrophil 5-lipoxygenase (5-LOX) in a dose-dependent manner; it specifically yields IC50 values of 7.8 +/- 1.7 for the production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4).
Synonym:
77175-51-0; Croconazol; Croconazolum; 1-(1-(2-((3-Chlorobenzyl)oxy)phenyl)vinyl)-1H-imidazole; 1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]imidazole; 1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]vinyl]imidazole; 1H-Imidazole, 1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-
CAS No.:
77175-51-0
Compound CID:
2880
Formula:
C18H15ClN2
Formula Weight:
310.78
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Croconazole can be used in microbiological research to examine the antifungal activity of imidazole derivatives.
Library Information
Target:
Lipoxygenase; LTR
Receptor:
5-LOX; LTB4 receptor
Pathways:
Immunology/Inflammation; Metabolism
Plate Number:
AOCL-11
Plate Location:
b10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 160.89 mM
Special Max Solubility:
Methanol: 1.55 mg/mL (4.99 mM); Acetonitrile: 1.55 mg/mL (4.99 mM)
